Rationale of the treatment of hydrofluoric acid burns.

نویسندگان

  • S A Carney
  • M Hall
  • J C Lawrence
  • C R Ricketts
چکیده

Carney, Shirley A., Hall, M., Lawrence, J. C., and Ricketts, C. R. (1974). British Journal of Industrial Medicine, 31, 317-321. Rationale of the treatment of hydrofluoric acid burns. On contact with skin hydrofluoric acid yields hydrogen and fluoride ions, which exhaust the tissue's buffering capacity. Fluoride was found to be toxic to skin cells, as judged by the accumulation of 3-phosphoglycerate (3-PG), at about 2 x 10-3 mol/l fluoride ion in the medium on which skin slices were maintained. This toxicity was reversible by the dilution brought about by transfer of the skin to a fresh medium; 3-PG levels fell and tetrazolium reductase measurements showed adequate viability. Using a specific ion electrode for fluoride, the efficacy of calcium, magnesium and lanthanum salts and hyamine in lowering fluoride ion concentration in the presence of serum was examined. Lanthanum was the most effective but was itself toxic to skin cells as judged by respiration and tetrazolium reductase measurements. Calcium appeared more effective as chloride than as gluconate. Magnesium and hyamine were ineffective under the conditions of experiment. In the presence of serum, calcium gluconate is only just capable of lowering the concentration of fluoride ions to the level at which their toxic effect is negligible. The importance of rapid removal of hydrofluoric acid from the skin surface as a first-aid treatment is emphasized.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

A review of hydrofluoric acid burn management.

Hydrofluoric acid (HF) causes a unique chemical burn. Much of the current treatment knowledge of HF burns is derived from case reports, small case series, animal studies and anecdotal evidence. The management can be challenging because clinical presentation and severity of these burns vary widely. Plastic surgeons managing burn patients must have a basic understanding of the pathophysiology, th...

متن کامل

Effect of hydrofluoric acid concentration and etching time on microtensile bond strength of suprinity and enamic CAD/CAM ceramics to resin cement

Introduction: The use of dental ceramics has increased due to their beauty and biocompatibility. The aim of this study was to evaluate the effect of hydrofluoric acid concentration and etching time on microtensile bond strength (μTBS) of the Enamic and Suprinity ceramics. Material & Methods: In this in vitro study, two hydrofluoric acid (HFA) concentrations of 5% (A) and 10% (B) were used at t...

متن کامل

Burns caused by dilute hydrofluoric acid in the bleach.

Two male cleaning workers aged 62 (patient 1) and 28-(patient 2) presented with red, swollen, aching hands and fingers. At the first interview, the fingers of the right hand of both patients were swollen from the proximal interphalangeal joint to the tip of the finger. The fingers were red and intensely painful. The bleach that both patients used contained 9.5% hydrofluoric acid, and therefore ...

متن کامل

Hydrofluoric acid burns from a household rust remover.

TO THE EDITOR: The report by Mangion et al draws attention to a serious risk in the environment. The general public has been increasingly protected against the risk of harm from domestic products by a combination of legal liability actions and government regulation. Thus, the continuing availability to the general public of hydrofluoric acid (HF) in concentrations that are hazardous is somethin...

متن کامل

Hydrofluoric Acid Exposure

A 21-year-old male was admitted to the emergency department with bleeding skin burns. He had been exposed to 70% hydrofluoric acid (HF) through his nitrile hand gloves during an etching glass procedure at work. He had painful lesions, which included bleeding skin abrasions due to seconddegree burns on the first and second fingertips on the right hand, and white spots on the left first finger, w...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • British journal of industrial medicine

دوره 31 4  شماره 

صفحات  -

تاریخ انتشار 1974